Steve Bannon, the former White House chief strategist who backed Moore's candidacy, condemned the Washington Post as part of the "opposition party" after it made the allegations public.
But she also told reporters: "The president also believes that if these allegations are true, Judge Moore will do the right thing and step aside".
Moore, a 70-year-old former state Supreme Court justice, has defiantly denied allegations of decades-old sexual misconduct with minors.
Fifty-four percent of Alabama voters suggested that Moore should not resign given the current allegations from the Washington Post. During a second incident, Corfman says Moore allegedly took off her clothes and touched her over her underwear.
He denies the women's reports and says he won't quit the race.More news: Facebook wants you to send them your nude picture. But why?
In the small eastern Alabama town of Heflin, a handful of people interviewed by the AP indicated they were indifferent to the allegations if not disbelieving of them.
Three other women said they had similar experiences with Moore when they were teenagers.
Stewart came to the floor and told McConnell and unusual that a statement was being sent to reporters. He told potential donors that he is counting on the help of "God-fearing conservatives like you to stand with me at this critical moment".
"These allegations are completely false and are a desperate political attack by the National Democrat Party and the Washington Post on this campaign", Moore said in a statement.
The statement also notes that Moore has been married to the same woman for 33 years and has four children and five grandchildren. "They're out to destroy him", Bannon continued, and then asked rhetorically: "Do you know why?"More news: United States ground invasion of North Korea could cost 'millions' of lives
Officials in Alabama said the opinions of national Republican leaders would have little effect on the state party.
In Washington, Republican senators responded to the report with shock and dismay, telling reporters that if the claims were true, Moore should exit the race immediately. In a campaign news release at the time, Harris described Moore as someone who would bring "principle to the Senate" and said he had a "backbone of steel".
Moore is running against Democrat Doug Jones in a special election to succeed Jeff Sessions, who left the Senate to become USA attorney general.
"Herman Cain's going up in the polls, then the day he gets out - nothing", said Hannity, referring to a wave of 2011 sexual harassment relevations that sunk the Republican businessman's presdental bid. He's not going to like Roy Moore because Shelby was a Democrat for a long time.
Other Republican senators weighing in included Jeff Flake of Arizona, David Perdue of Georgia, John Thune of South Dakota, Lisa Murkowski of Alaska, Cory Gardner of Colorado, Richard Shelby of Alabama and Patrick Toomey of Pennsylvania. Sen.
Ziegler contends that the allegations against Moore are unlikely to impact his political run as he never had "sexual intercourse" with the 14-year-old girl in question, their relationship "happened nearly 40 years ago", and finally, "Moore fell in love with one of the younger women", namely his wife Kayla. And if you're down to arguing about the age of consent in an allegation involving a 32-year-old man and a 14-year-old girl, you've already lost that argument.More news: BlizzCon 2017: Overwatch to Get New Hero Moira, New BlizzardWorld Map Soon
But nationally, GOP leaders were less likely to defend Moore's actions and more likely to say the allegations were disturbing, without necessarily ruling on their veracity.